Rectal cancer
Efficacy of Hyperthermic Intraperitoneal Chemotherapy
Where to go
1 hospital in India taking patients for this trial.
Registry summary (technical)
A dose titration study and a combined superiority registry-based open-label randomized control trial is planned to answer the trial objectives. The study will be registry-based to allow simpler and more comprehensive follow-up. Patients with colorectal cancer will be treated with cytoreductive surgery (CRS) together with either standard oxaliplatin HIPEC (the control for the efficacy study) or oxaliplatin/irinotecan HIPEC in combination with 5-FU 24-hour EPIC. The 5-FU will be administered postoperatively when the abdomen is completely sutured. The drug is divided equally into 2 injections of …
Sponsor: Uppsala University
NCT04861558 on ClinicalTrials.gov
Last updated on the registry 30 May 2025 · read by us 20 Oct 2026