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Home › Trials › Lung

Lung cancer (non-small cell)

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

Who can joinAdults
Age18+ years
Kind of studyPhase 3: compared with usual treatment
What it testsA medicine
The full list of who can and cannot join is on the registry. Ask the trial team, or write to us and we will explain it in simple words.

Where to go

6 hospitals in India taking patients for this trial.

Spandana Oncology Centre (SOC)Bengaluru, KarnatakaDirections ↗
Tata Memorial HospitalMumbai, MaharashtraDirections ↗
Sahyadri Super Speciality HospitalPune, MaharashtraDirections ↗
Bhakti Vedanta Hospital and Research InstituteThane, MaharashtraDirections ↗
Venkateshwar HospitalNew Delhi, National Capital Territory of DelhiDirections ↗
Fortis HospitalNew Delhi, National Capital Territory of DelhiDirections ↗
Registry summary (technical)

The purpose of the study is to compare how the new combination treatment (Sigvotatug Vedotin plus pembrolizumab) works compared to pembrolizumab alone in patients with non-small cell lung cancer (NSCLC) with high levels of PD-L1. This is a protein that acts as a kind of "brake" to keep the body's immune responses under control. The study is seeking for participants who: * Are confirmed to have NSCLC (Stage 3 or 4). * Have PD-L1 levels in more than 50% of the cancer cells. All participants in this study will receive pembrolizumab at the study clinic once every 6 weeks as an intravenous (IV) …

Sponsor: Pfizer
NCT06758401 on ClinicalTrials.gov
Last updated on the registry 25 Sep 2026 · read by us 20 Oct 2026

Need help reaching the trial team? Write to us.

Tell us the city, the type of cancer and the trial number if you have one. We reply in simple words within 3 working days.

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