ବ୍ରେନ୍ ଟ୍ୟୁମର୍ (ଗ୍ଲିଓମା)

Paediatric H3K27/H3G34 mutant diffuse midline gliomas are high grade gliomas that arise in midline structures/cerebral hemispheres and are known to have dismal outcomes. Standard treatment includes definitive radiation therapy to primary site along with concurrent temozolomide chemotherapy following histological confirmation with a biopsy. Studies have shown poorer outcomes in the paediatric age group compared to that of adults and an increased risk to fail/recur in the leptomeninges(covering of brain and spinal cord). The following study is planned in order to assess the benefit of craniospin…

Sponsor: Tata Memorial Centre
NCT06720727 on ClinicalTrials.gov
Last updated on the registry 20 Jan 2025 · read by us 20 Oct 2026