Brain tumour (glioma)
Craniospinal Irradiation in Histone AlteRed Midline Glioma
Where to go
1 hospital in India taking patients for this trial.
Registry summary (technical)
Paediatric H3K27/H3G34 mutant diffuse midline gliomas are high grade gliomas that arise in midline structures/cerebral hemispheres and are known to have dismal outcomes. Standard treatment includes definitive radiation therapy to primary site along with concurrent temozolomide chemotherapy following histological confirmation with a biopsy. Studies have shown poorer outcomes in the paediatric age group compared to that of adults and an increased risk to fail/recur in the leptomeninges(covering of brain and spinal cord). The following study is planned in order to assess the benefit of craniospin…
Sponsor: Tata Memorial Centre
NCT06720727 on ClinicalTrials.gov
Last updated on the registry 20 Jan 2025 · read by us 20 Oct 2026