মুখৰ কেন্সাৰ
Newer Therapeutic Targets in Head and Neck Cancers
ক’ত যাব
ভাৰতৰ 1 খন হস্পিতালত এই trial-ৰ বাবে ৰোগী ভৰ্তি কৰা হৈছে।
ৰেজিষ্ট্ৰীৰ সাৰাংশ (কাৰিকৰী)
Based on the recently identified mutations in HNSCCs, the major pathologic pathways implicated in the tumorigenesis of HNSCC include dysregulation of four processes: 1. cellular survival and proliferation (e.g., TP53, EGFR, MET, and PIK3CA); 2. cell-cycle control (e.g., CDKN2A and CCND1); 3. cellular differentiation (e.g., NOTCH1); and 4. Adhesion and invasion signaling (e.g., FAT1).7 TP53, EGFR, PIK3CA, CDKN2A, CCND1, and MET participate in several common signaling pathways. Alterations of these genes are most frequently seen in alcohol and tobacco-related HNSCC. However their role in progn…
স্পন্সৰ: বেনাৰস হিন্দু ইউনিভাৰ্চিটি
ClinicalTrials.gov-ত NCT05382585
ৰেজিস্ট্ৰিত অন্তিম আপডেট 13 Aug 2024 · আমাৰ দ্বাৰা 20 Oct 2026-ত পঢ়া হৈছে