Mouth cancer
Newer Therapeutic Targets in Head and Neck Cancers
Where to go
1 hospital in India taking patients for this trial.
Registry summary (technical)
Based on the recently identified mutations in HNSCCs, the major pathologic pathways implicated in the tumorigenesis of HNSCC include dysregulation of four processes: 1. cellular survival and proliferation (e.g., TP53, EGFR, MET, and PIK3CA); 2. cell-cycle control (e.g., CDKN2A and CCND1); 3. cellular differentiation (e.g., NOTCH1); and 4. Adhesion and invasion signaling (e.g., FAT1).7 TP53, EGFR, PIK3CA, CDKN2A, CCND1, and MET participate in several common signaling pathways. Alterations of these genes are most frequently seen in alcohol and tobacco-related HNSCC. However their role in progn…
Sponsor: Banaras Hindu University
NCT05382585 on ClinicalTrials.gov
Last updated on the registry 13 Aug 2024 · read by us 20 Oct 2026